Principal Investigator- Dr. Anuraj Nayarisseri
Post- Research Analyst
Duration- July 2020 - Jan 2021
Technical expertise:
- Genomics analysis: Gene finding from Virus, Prokaryotes and Eukaryotes, Gene sequence analysis, FASTA/FLAT file Gb analysis, Annotation of genes and genomes, Molecular weight analysis of gene, GC% , AT%, Nucleotide composition, Restriction Enzymes analysis, Primer Designing, Probe Designing, cDNA Conversion, Introns and exons analysis, SNP analysis, EST analysis, Poly-A tail analysis, SSR analysis (microsatellites/mini satellites), STS analysis, Promoter analysis, Transcription start site analysis, UTR analysis, Fuzzy techniques, Sequence chopping analysis, Pairwise alignment, Multiple sequence alignment, local alignment, global alignment, Conserved region analysis, Phylogenetic analysis, Distance matrices analysis, Neighbor Joining, Dynamic programming.
- Proteomics analysis: Protein Coding Regions prediction(CDS), Protein amino acid composition, Molecular weight analysis, Iso electric point, Biochemical studies such as hydrophobic , hydrophilic, polar, non-polar, positive residues, negative residues, Aromatic analysis, aliphatic residues, Protein Primary structure prediction, Protein secondary structure prediction, Protein Motif and domain analysis, Protein structure retrieval and analysis, Protein 3D structure mutagenesis, Protein Structure Ramachandran Mapping, Loop Modeling, Side chain modelling, Protein 3D structure modeling and Structure Validation, Protein Cavity Prediction. Protein Structure comparison.
- Drug Designing techniques: Molecular Modeling of Drug and other chemical compounds, Ligand preparation, Physicochemicalproperties of drugs analysis, Molecular docking, Pharmacophore studies, Lipinski’s Rule of 5, ADMET Studies, Virtual Screening.
- Programming languages- R and Python.
- NGS Analysis, Shell scripting, RNA Seq, DnaSeq, Exome analysis, variant calling .